Category: Disease States

Disease States

New AI Test Estimates Individualized Chemotherapy Benefit in Breast Cancer Patients

Using causal artificial intelligence and digital pathology, the test moves beyond population-level averages to predict patient-specific chemotherapy outcomes.

Lunit, CellCarta Partner to Advance AI-Powered Digital Pathology for Companion Diagnostics
Concussion Blood Test Advances Toward FDA Submission With Point-of-Care Collaboration
Nucleosome Levels Found Elevated in Trauma Patients at Risk for Blood Clots, Mayo Clinic Study Shows
FDA Grants CLIA Waiver for Rapid Test That Differentiates Bacterial and Non-Bacterial Respiratory Infections
DPYD Testing Gaps Leave Colorectal Cancer Patients at Risk for Severe Drug Toxicity
CSF Liquid Biopsy Delivers 82% Clinical Impact Rate in CNS Lymphoma Cases
Liquid Biopsy Technology Detects Over 95% of Early-Stage Cancers in Blinded Validation Study
Nucleosome Liquid Biopsy Shows Promise for Lung Cancer Risk Stratification
Gene Expression Profile Test Identifies High-Risk Melanoma Patients Missed by Traditional Methods

Disease States

C2N Diagnostics’ eMTBR-tau243 Plasma Assay Used in Alzheimer’s Phase 3 Trial Dataset

The biomarker showed independent associations with cognitive and functional decline, offering complementary information alongside p-tau217 in early symptomatic Alzheimer's disease.

Disease States

Diabetes Testing Moves Earlier—and Gets More Complex

As the 2026 ADA Standards of Care emphasize earlier identification and more precise classification of diabetes, clinical laboratories are rethinking workflows, assay menus, and their role in detection.

Cancer

Ibex Medical Analytics Launches Next-Generation AI Pathology Platform

Ibex Medical Analytics has launched Ibex 4, an AI-powered pathology platform with expanded end-to-end breast cancer diagnostic workflows, zero-click IHC tools, and enhanced lab integration capabilities for increased efficiency.

Infectious Diseases

Breath Test Using Carbon Isotopes May Quickly Confirm Bacterial Infections

A proof-of-concept study shows that bacteria-metabolized molecules enriched with carbon-13 produce detectable exhaled CO2, enabling rapid infection identification with inexpensive infrared scanners.

Womens Health

WHOOP Adds Women’s Health Blood Biomarker Panel to Its Lab Testing Lineup

The new panel includes 11 female-specific biomarkers covering hormonal transitions, thyroid function, and nutrient levels.

Allergy & Autoimmune

Skin Patch Opens New Door for Immune Monitoring

Researchers at JAX and MIT have developed a microneedle patch that samples immune cells from skin within hours, providing a noninvasive alternative to blood draws and biopsies.

Cardiovascular, Cerebrovascular

Updated Guideline Issued on Lipid and Cholesterol Management, Expanding Role of Key Biomarker Tests

The ACC, AHA, and nine other associations have issued an updated dyslipidemia guideline, recommending earlier intervention and expanded use of lipoprotein(a) and apolipoprotein B testing to improve cardiovascular risk assessment.

Dementias & Alzheimer’s

Researchers Develop First DNA Aptamers That Bind Alzheimer’s Blood Biomarker Neurofilament Light Chain

The newly identified aptamers match antibody-level binding strength and could support the development of lower-cost, point-of-care blood tests for neurodegeneration.

Diabetes & Metabolic Diseases

New Blood Test Score Identifies Hidden Alcohol-Related Liver Disease

Researchers at UC San Diego have developed the MAPI score, a blood test using five standard lab values to distinguish alcohol-related liver injury from metabolic causes, according to a study in Gastroenterology.

Kidney Disease

Insight Molecular Diagnostics Nears FDA Submission for Kidney Transplant Rejection Test Kit

Insight Molecular Diagnostics has completed clinical validation and received ISO 13485 certification for its GraftAssureDx kidney transplant rejection test kit, moving toward FDA submission, according to the company.

Respiratory Disease

Yourgene Health Cystic Fibrosis Assay Receives IVDR Accreditation

The Cystic Fibrosis Base assay has received IVDR accreditation, ensuring high standards for detecting cystic fibrosis mutations.

Sepsis

Study Finds Test Helps Distinguish Infection From Inflammation in Bone Marrow Transplant Patients

Research in bone marrow transplant patients with blood cancers and febrile neutropenia suggests the host-response test may help identify infection in high-risk populations.