The collaboration enables direct ordering of UNITY Complete and Northstar tests within Epic’s system, with results flowing back to electronic health records.
BillionToOne Inc has announced a collaboration with Epic to integrate its prenatal and oncology testing portfolio with Epic’s Aura diagnostics suite, allowing clinicians to order tests directly within the electronic health record system.
The agreement, signed in December 2025, enables healthcare providers to order BillionToOne’s UNITY Complete prenatal test as well as Northstar Select and Northstar Response liquid biopsy tests through Epic’s platform. Test results then flow back into the electronic health record, where they can support clinical decision-making and streamline workflows for health systems, community practices, maternal-fetal medicine practices, and oncology clinics.
“Collaborating with Epic advances our goal of making high-quality molecular diagnostics easier to access and simpler to use in everyday clinical care,” says Oguzhan Atay, co-founder and CEO of BillionToOne, in a release. “By integrating our tests directly into the EHR, we’re helping clinicians spend less time navigating logistics and more time focusing on patient care, whether supporting expectant families or guiding cancer treatment decisions.”
Test Portfolio Integration
UNITY Complete is a clinically validated non-invasive prenatal test that provides direct fetal risk assessment for up to 14 recessive and X-linked conditions, aneuploidies, and other conditions from a single maternal blood sample. The company’s oncology offerings include Northstar Select, which helps identify appropriate therapies for patients with advanced cancer, and Northstar Response, which enables treatment monitoring over time.
With results delivered directly into Epic and available through the MyChart patient portal, the integration aims to support faster clinical decision-making and improve the patient experience.
“BillionToOne’s use of Aura integrates oncology and prenatal tests and results where they matter—inside the clinician’s workflow, at the moment of decision,” says Seth Hain, senior vice president of research and development at Epic, in a release.
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