Cerilliant has released new antifungal Certified Spiking Solutions of fluconazole, itraconazole, voriconazole, posaconazole, 5-fluorocytosine, and ketoconazole at a 2.0 mg/mL concentration. These certified reference materials (CRMs) may be used as Snap-N-Spike starting materials to prepare calibrators, controls, or linearity standards for LC-MS/MS testing of antifungals in therapeutic drug monitoring (TDM).

Use of LC-MS/MS methods for TDM of antifungals requires highly pure CRMs to ensure valid clinical outcomes and guarantee a test’s accuracy and reproducibility. Cerilliant’s Certified Spiking Solutions meet industry standards including ISO Guide 34, ISO 17025, and ISO 13485, and are suitable for applications ranging from TDM, diagnostic testing, and endocrinology, to toxicology, forensic testing, and clinical chemistry.

“Calibrators for LC-MS/MS methods are critical to the accuracy of results and must be carefully evaluated,” said Josh Cooper, PhD, Cerilliant’s supervisor for analytical R&D. “It is important to use fully characterized materials to properly adjust for any chromatographic or residual impurities present. At Cerilliant, we are very sensitive to the intended use of our certified spiking solutions and characterize our CRMs accordingly.”

For more information, visit Cerilliant.