pn18.jpg (5957 bytes)This latex-enhanced immunoturbidimetric assay for the quantitative determination of C-reactive protein in serum allows the user to measure CRP from 0.08 – 160 mg/L, giving the laboratory the ability to consolidate two different tests into one.
     C-reactive protein is present in serum of normal individuals at levels between 0-5mg/l. Levels above this are associated with acute phase response to infection, tissue injury, inflammatory disorders and associated diseases. The rise in concentration of CRP occurs much earlier (in four to six hours) than for other acute phase reactants which usually take more than 24 hours to produce a detectable signal in serum. In addition CRP levels return to normal quickly at the end of the acute episode. Measurement of CRP aids in evaluation of the amount of injury to body tissues.
     Research has indicated that CRP levels within the normal range can be used for the assessment of cardiovascular risk in high-risk individuals.
Keywords: cardiac markers, inflammation, CRP