Category: Disease States

Disease States

Castle Biosciences Launches Test to Guide Atopic Dermatitis Treatment Selection

The gene expression test is designed to identify patients more likely to respond to JAK inhibitors versus Th2-targeted therapies.

Disease States

FDA Grants Breakthrough Designation for Axial Spondyloarthritis Diagnostic Test

The multiplex immunoassay measures autoantibodies to the 14-3-3eta protein and aims to reduce diagnostic delays that currently average seven to 10 years.

Disease States

Blood Test Shows Promise for Earlier ALS Detection

UCLA Health researchers find cell-free DNA combined with machine learning can distinguish ALS from other neurological conditions.

Cancer

Study Validating Esophageal Cancer Test Accepted by Gastroenterology Journal

The mass spectrometry-based assay achieved 100% sensitivity in detecting patients who later progressed to cancer in a blinded cohort study.

Infectious Diseases

UCF Researchers Develop Multiplex Biosensor for HIV and Hepatitis Detection

Electrochemical biosensor aims to simultaneously detect HIV, Hepatitis B, and Hepatitis C in resource-limited settings using RNA-level identification.

Womens Health

Preexisting High Cholesterol in Pregnancy Linked to Elevated CV Risk

Researchers urge clinicians to integrate lipid management into prenatal care to mitigate elevated obstetric complications and cardiovascular risks.

Allergy & Autoimmune

Why Laboratory Insights Are Critical During Asthma Peak Week

From rising demand for comprehensive IgE profiles to the emergence of molecular allergen diagnostics, laboratories are central to how clinicians prepare for and manage September’s asthma spike.

Cardiovascular, Cerebrovascular

Sixth-Generation Troponin T Test Shows High Accuracy for Heart Attack Diagnosis

Study of more than 13,000 individuals demonstrates improved precision for emergency department triage and patient outcomes.

Dementias & Alzheimer’s

New FDA-Cleared Blood Test Moves Alzheimer’s Assessment into Primary Care

Roche's Elecsys pTau181 assay gives clinical labs a key role in the initial evaluation of cognitive decline, helping to rule out amyloid pathology earlier in the diagnostic process.

Diabetes & Metabolic Diseases

FDA Clears Next-Generation HbA1c Analyzer with 50-Second Results

The automated system uses ion exchange HPLC technology to deliver A1c results while detecting common hemoglobin variants.

Kidney Disease

Carna Health, Siemens Healthineers Partner on AI-Enabled CKD Platform

The agreement aims to improve early detection and management of chronic kidney disease in underserved populations through integrated diagnostics and digital health solutions.

Respiratory Disease

Yourgene Health Cystic Fibrosis Assay Receives IVDR Accreditation

The Cystic Fibrosis Base assay has received IVDR accreditation, ensuring high standards for detecting cystic fibrosis mutations.

Sepsis

AI-Powered Sepsis Test Shows Promise in Large Clinical Study

TriVerity system demonstrated high sensitivity and specificity across more than 1,200 patients in pivotal SEPSIS-SHIELD trial.