Category: Disease States

Disease States

FDA Approves Companion Diagnostic for Colorectal Cancer Treatment

The FDA has approved a companion diagnostic for identifying BRAF V600E-mutant metastatic colorectal cancer patients eligible for encorafenib combination therapy.

Disease States

Labcorp Expands MRD Testing Portfolio for Three Cancer Types

Labcorp has expanded its MRD testing portfolio with new personalized panels for breast and lung cancer and nationwide whole-genome MRD testing for stage III colon cancer, enabling earlier detection of recurrence via ctDNA analysis.

Disease States

Blood Test Shows Obesity Speeds Alzheimer’s Development

A longitudinal study finds blood-based biomarkers more sensitive than PET scans in detecting obesity's impact on Alzheimer's pathology.

Cancer

Human Longevity Expands $1M Cancer Pledge to Include Colon Cancer

The biotechnology company's integrated screening approach combines whole-genome sequencing, imaging, and multiple biomarker tests to enable early detection.

Infectious Diseases

Altona Diagnostics Completes Automated PCR Portfolio for All Five Hepatitis Viruses

The new PCR test detects and quantifies hepatitis delta virus (HDV)-specific RNA in human EDTA plasma and serum.

Womens Health

ADLM Clinical Chemistry Journal Features Maternal-Fetal Diagnostics

Special issue explores advances in noninvasive prenatal screening, molecular diagnostics, and care disparities affecting perinatal outcomes.

Allergy & Autoimmune

Tear-Based Diagnostic Test for Red Eye Conditions Enters Clinical Study

The test is being developed to differentiate between adenoviral conjunctivitis, herpetic keratitis, and allergic conjunctivitis at the point of care.

Cardiovascular, Cerebrovascular

New Urine Test Offers Faster, Cheaper Diagnosis for Inherited Nerve Disorder

The test measures two sugar alcohols to detect SORD-related neuropathy, which standard genetic tests sometimes miss.

Dementias & Alzheimer’s

Study Links Fat Transport Molecules to Alzheimer’s Risk Based on Genetics

Research finds lysophosphatidylcholines either promote or protect against disease depending on APOE ε4 gene status, with implications for personalized treatments.

Diabetes & Metabolic Diseases

FDA Clears Next-Generation HbA1c Analyzer with 50-Second Results

The automated system uses ion exchange HPLC technology to deliver A1c results while detecting common hemoglobin variants.

Kidney Disease

Carna Health, Siemens Healthineers Partner on AI-Enabled CKD Platform

The agreement aims to improve early detection and management of chronic kidney disease in underserved populations through integrated diagnostics and digital health solutions.

Respiratory Disease

Yourgene Health Cystic Fibrosis Assay Receives IVDR Accreditation

The Cystic Fibrosis Base assay has received IVDR accreditation, ensuring high standards for detecting cystic fibrosis mutations.

Sepsis

Rapid Sepsis Test Reduces Mortality by 42% in Academic Medical Center Study

The eight-minute test also shortened hospital stays by nearly two days at Froedtert Hospital, reinforcing previous multi-site evidence.