Can an Alzheimer’s Blood Test Detect Early, Subtle Cognitive Decline?
Biomarkers in midlife adults without dementia may be linked to the earliest signs of waning cognition, researchers found.
Tag: biomarkers
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Liquid Biopsy of Tumor Microenvironment Predicts Cancer Therapy Response
LiquidCell Dx has published research in Nature on LiquidTME, a blood-based assay that profiles the tumor microenvironment and predicts immunotherapy response, potentially offering a noninvasive alternative to tissue biopsy.
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New Clinical Data Supports Blood-Based Monitoring for Cancer Treatment Response
Personalis presented data at AACR showing its NeXT Personal assay enabled ultrasensitive ctDNA monitoring for colorectal and lung cancer patients, demonstrating 100% sensitivity at baseline and 100% specificity for relapse post-surgery.
Biognosys and Michael J. Fox Foundation Partner to Develop Parkinson’s Disease Biomarkers
The collaboration focuses on creating sensitive assays for a common genetic risk factor to guide drug development and clinical trials.
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Maternal Blood Test Identifies Autoantibodies Linked to Autism Subtype
The diagnostic tool identifies a specific biological cause of autism with more than 97% predictive accuracy.
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Roche Receives CE Mark for Multiple Sclerosis Blood Test
The Elecsys NfL test measures a protein associated with nerve cell injury to monitor disease activity in patients with relapsing remitting multiple sclerosis.
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Blood-Based Biomarker Identifies Cancer Risk in Lynch Syndrome Patients
Researchers at MD Anderson have identified a blood-based biomarker using T cell receptor sequencing that may help assess cancer risk in asymptomatic Lynch syndrome carriers, according to a study in Nature Communications.
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Trinity Biotech and University at Buffalo Partner to Commercialize Sjögren’s Syndrome Biomarkers
The collaboration focuses on advancing proprietary biomarkers for the earlier and more accurate detection of the autoimmune disease.
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AI-Enhanced Blood Test Improves Early Detection of Leprosy
The diagnostic method combines a multi-antibody blood test with an artificial intelligence-supported questionnaire to identify cases before severe symptoms appear.
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Multi-Cancer Early Detection Test Added to Evexia Diagnostics Platform
20/20 BioLabs’ AI-powered multi-cancer early detection test, OneTest for Cancer, is now available to approximately 40,000 clinicians via the Evexia Diagnostics platform.
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New Program Aims to Fill Long COVID Diagnostic Gap With Validated Tests
PolyBio Research Foundation has launched a $1.35 million program at UCSF to compare and validate diagnostic tests for long COVID, aiming to address the lack of standardized clinical diagnostics in the field.
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Blood Test May Improve Risk Assessment for HPV-Related Throat Cancer
Research identifies how circulating tumor DNA can inform personalized treatment and surveillance strategies.
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NIH Awards $850,000 to Support Menstrual Blood Test for Endometriosis
The NIH has awarded $850,000 to Northwell Health’s Feinstein Institutes to advance a noninvasive menstrual blood test for endometriosis, aiming to reduce reliance on surgical diagnosis, according to the institutes.
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Concussion Blood Test Advances Toward FDA Submission With Point-of-Care Collaboration
BRAINBox Solutions reports near-completion of its HeadSMART II trial for a concussion blood test, supporting an upcoming FDA submission, and advances in a point-of-care biomarker collaboration with Prolight Diagnostics.
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FDA-Approved PD-L1 Companion Diagnostic Expanded to Esophageal and GEJ Carcinoma
The companion diagnostic can now help identify patients with esophageal or gastroesophageal junction carcinoma who may be eligible for pembrolizumab treatment.
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Nucleosome Liquid Biopsy Shows Promise for Lung Cancer Risk Stratification
Preoperative blood testing using H3K27Me3-nucleosome levels may help clinicians identify which non-small cell lung cancer patients need closer follow-up or additional treatment.
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C2N Diagnostics’ eMTBR-tau243 Plasma Assay Used in Alzheimer’s Phase 3 Trial Dataset
The biomarker showed independent associations with cognitive and functional decline, offering complementary information alongside p-tau217 in early symptomatic Alzheimer’s disease.
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Largest Lung Nodule Biomarker Validation Study Backs Earlier Cancer Detection
A pooled analysis of more than 1,100 patients across four cohort studies supports the clinical utility of the Nodify CDT test in identifying high-risk lung nodules.
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