Category: Disease States

Disease States

GeneCentric Data Suggest Fragmentomics Could Expand Liquid Biopsy Beyond Mutation Testing

Presentations at AACR 2026 will showcase fragmentomics-based technology for detecting therapeutic markers and providing prognostic insight.

Disease States

AI-Enhanced Blood Test Improves Early Detection of Leprosy

The diagnostic method combines a multi-antibody blood test with an artificial intelligence-supported questionnaire to identify cases before severe symptoms appear.

Disease States

Diabetes Testing Moves Earlier—and Gets More Complex

As the 2026 ADA Standards of Care emphasize earlier identification and more precise classification of diabetes, clinical laboratories are rethinking workflows, assay menus, and their role in detection.

Cancer

Home HPV Self-Sampling Kits Show Promise for Closing Cervical Screening Gap in Disabled Women

A new survey-based study finds that more than half of physically Disabled women would prefer at-home human papillomavirus testing over traditional clinic-based cervical screening.

Infectious Diseases

New Program Aims to Fill Long COVID Diagnostic Gap With Validated Tests

PolyBio Research Foundation has launched a $1.35 million program at UCSF to compare and validate diagnostic tests for long COVID, aiming to address the lack of standardized clinical diagnostics in the field.

Womens Health

NIH Awards $850,000 to Support Menstrual Blood Test for Endometriosis

The NIH has awarded $850,000 to Northwell Health’s Feinstein Institutes to advance a noninvasive menstrual blood test for endometriosis, aiming to reduce reliance on surgical diagnosis, according to the institutes.

Allergy & Autoimmune

Skin Patch Opens New Door for Immune Monitoring

Researchers at JAX and MIT have developed a microneedle patch that samples immune cells from skin within hours, providing a noninvasive alternative to blood draws and biopsies.

Cardiovascular, Cerebrovascular

Updated Guideline Issued on Lipid and Cholesterol Management, Expanding Role of Key Biomarker Tests

The ACC, AHA, and nine other associations have issued an updated dyslipidemia guideline, recommending earlier intervention and expanded use of lipoprotein(a) and apolipoprotein B testing to improve cardiovascular risk assessment.

Dementias & Alzheimer’s

Gut-Derived Blood Markers May Detect Early Cognitive Decline Before Symptoms

Researchers at the University of East Anglia report that gut-derived blood markers may help detect early cognitive decline before symptoms, according to findings published in Gut Microbes.

Diabetes & Metabolic Diseases

New Blood Test Score Identifies Hidden Alcohol-Related Liver Disease

Researchers at UC San Diego have developed the MAPI score, a blood test using five standard lab values to distinguish alcohol-related liver injury from metabolic causes, according to a study in Gastroenterology.

Kidney Disease

Insight Molecular Diagnostics Nears FDA Submission for Kidney Transplant Rejection Test Kit

Insight Molecular Diagnostics has completed clinical validation and received ISO 13485 certification for its GraftAssureDx kidney transplant rejection test kit, moving toward FDA submission, according to the company.

Respiratory Disease

Yourgene Health Cystic Fibrosis Assay Receives IVDR Accreditation

The Cystic Fibrosis Base assay has received IVDR accreditation, ensuring high standards for detecting cystic fibrosis mutations.

Sepsis

Sepsis Diagnostic Test Shapes ED Physician Decision-Making, Study Finds

A multicenter, vignette-based study found that adding a rapid sepsis test result to standard clinical data changed or reinforced diagnostic decisions in 86% of cases.